”Our study confirms that levels of major carcinogens are markedly reduced in the emissions of the analyzed HNB product in relation to the conventional tobacco cigarettes…”

Mallock et al., Levels of selected analytes in the emissions of “heat not burn” tobacco products that are relevant to assess human health risks. Archives of Toxicology, 2018. 92(6):2145-2149. 

”In particular, through the FDA’s scientific evaluation of the company’s applications, peer-reviewed published literature and other sources, the agency found that the aerosol produced by the IQOS Tobacco Heating System contains fewer toxic chemicals than cigarette smoke, and many of the toxins identified are present at lower levels than in cigarette smoke. For example, the carbon monoxide exposure from IQOS aerosol is comparable to environmental exposure, and levels of acrolein and formaldehyde are 89% to 95% and 66% to 91% lower than from combustible cigarettes, respectively. 

Additionally, IQOS delivers nicotine in levels close to combustible cigarettes suggesting a likelihood that IQOS users may be able to completely transition away from combustible cigarettes and use IQOS exclusively. Available data, while limited, also indicate that few non-tobacco users would be likely to choose to start using IQOS, including youth.”

”As the exposure to compounds of concern in the aerosol is reduced compared to conventional cigarette smoke, it is likely that there is a reduction in risk, though not to zero, to health for smokers who switch completely to heat-not-burn tobacco products”

The UK Committee on Toxicity of Chemicals in Food, Consumer Products and the Environment (COT) references a 50–90% decrease in some of the harmful and potentially harmful compounds (HPHCs) in the aerosol generated by heat- not-burn devices which the user would be exposed to, compared to HPHCs from cigarette smoke. Statement on the toxicological evaluation of novel heat-not-burn tobacco products, The Committee on Toxicity of Chemicals in Food, Consumer Products and the Environment (COT), Department of Health UK, December 2017.

”Based on current knowledge, stating that vaping is at least 95% less harmful than smoking remains a good way to communicate the large difference in relative risk unambiguously so that more smokers are encouraged to make the switch from smoking to vaping.”

McNeill, A., Brose, L.S., Calder, R. et al. “Evidence review of e-cigarettes and heated tobacco products 2018”. Public Health England (2018).

”In alternative nicotine consumption patterns, such as vaping, snus or nicotine gums, there is no combustion. As a consequence, the consumption of these products should be considered as significantly less dangerous to health than the consumption of tobacco [containing] cigarettes.” – Swiss Federation of Addiction Professionals

Swiss Federation of Addiction Professionals, “Position of the federation of addiction professionals on vaping” (Translated from “Position de la fédération des professionnels des addictions sur le vapotage”), November 2017. les/171019_positionspapier_vapotage_0.pdf. 

”Although nicotine can be toxic, the overall scientific consensus is that the vast proportion of harm from tobacco comes from substances produced by combustion,”

Drope, J., Cahn, Z., Kennedy, R., Liber, A.C., Stoklosa, M., Henson, R. and Douglas, C.E. Key issues surrounding the health impacts of electronic nicotine delivery systems (ENDS) and other sources of nicotine. CA: a cancer journal for clinicians. 2017 Nov, 67(6): 449–71. Please note the research was published with the following disclaimer: “The contents of this article are the sole responsibility of the authors and do not necessarily represent the positions of the American Cancer Society.” according to researchers from the American Cancer Society.